In April 2025, Colossal Biosciences announced the direwolf is back after over 10,000 years! Males Romulus and Remus born Oct 2024, female Khaleesi in Jan 2025. 🐺✨
Colossal Biosciences announces direwolf de-extinction with three pups born
Key facts
- In April 2025, Colossal Biosciences announced the de-extinction of the direwolf, marking the first time in over 10,000 years the North American air heard the howl of a direwolf
- Scientists used ancient DNA from a 13,000-year-old tooth found in Ohio and a 72,000-year-old skull unearthed in Idaho
- Colossal performed a record 20 precise edits across 14 genes, with 15 genes identical to direwolf DNA and 5 edits for key direwolf traits
- Two male pups, Romulus and Reheis, were born on Oct 1, 2024
- A female pup named Kesi was born on Jan 30, 2025
- The pups are white-coated, larger, and more heavily built than greywolves
- The direwolf's howl had been absent from the planet for approximately 12,500 years
Sources
Colossal Biosciences Dire Wolf De-Extinctioncolossal.com
The Dallas-based de-extinction company produced three living dire wolves: Romulus and Remus, born October 1, 2024, and Khaleesi, born January 30, 2025, marking ...
Colossal Biosciences announces 'de-extinction' plan for ...cnn.com
Puppies resembling the extinct dire wolf were unveiled to the public by Colossal in April 2025. Three puppies were created using ancient DNA, ...
De-extinction Education - Colossal Biosciencescolossal.com
On April 7, 2025, Colossal Biosciences announced the successful rebirth of the dire wolf, marking the world's first de-extinction of an animal species.
Dire Wolf - Colossal Biosciencescolossal.com
On October 1, 2024, for the first time in human history, Colossal successfully restored a once-eradicated species through the science of de-extinction.
Scientists Revive the Dire Wolf, or Something Closenytimes.com
Colossal Biosciences appears to have done it, or something close, with the dire wolf, The animals will remain in captivity.
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