The Eleusinian Mysteries honored Demeter and Persephone with annual initiations involving a sacred drink called kykeon. A 2026 experiment showed that treating ergot in lye for 2 hours removed toxic ergopeptides while preserving psychoactive LSA compounds. Critics Shardai Mejia and Richard Ascough caution chemical feasibility isn't historical proof — no Eleusis vessel has yielded ergot residue.
2026 experiment tests ergot psychedelic theory for Eleusinian kykeon

Key facts
- The Eleusinian Mysteries were annual initiations at Eleusis near Athens honoring Demeter and Persephone, involving a sacred drink called kykeon.
- A 2026 experiment showed that treating 5% ergot powder in lye (wood ash, initial pH 12.5) for 2 hours removed detectable toxic ergopeptides while preserving psychoactive LSA and isoloa compounds.
- No vessel from Eleusis has yielded ergot residue, and no ancient recipe survives.
- Ergot appeared in a ritual context at Mas Castellar de Pontós sanctuary in Spain, associated with a cave sacred to a mother goddess.
- Critics Shardai Mejia and Richard Ascough argue chemical feasibility is not historical proof.
Site mentioned
Sources
Investigating the psychedelic hypothesis of kykeon ...nature.com
by RK Antonopoulos · 2026 · Cited by 3 — Tul., a fungus infecting cereals and producing ergot alkaloids (EAs), was the psychedelic agent in kykeon, the sacred elixir of the Eleusinian ...
(PDF) Investigating the psychedelic hypothesis of kykeon ...researchgate.net
Tul., a fungus infecting cereals and producing ergot alkaloids (EAs), was the psychedelic agent in kykeon, the sacred elixir of the Eleusinian ...
Did ancient Greek priestesses brew a mind-bending potion ...science.org
the researchers confirmed the priestesses could have brewed the kykeon from a parasitic fungus that grows on barley and can mimic the effects ...
Kykeonen.wikipedia.org
It is widely believed that kykeon refers to a psychoactive brew, as in the case of the Eleusinian Mysteries. A kykeon was used at the climax of the Eleusinian ...
Eleusinian Mysteriesen.wikipedia.org
The Eleusinian Mysteries were initiations held every year for the cult of Demeter and Persephone based at the Panhellenic Sanctuary of Eleusis in ancient ...
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